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Larry Leung

COO and Founder of Gray Box Biology LLC
Creating simple solutions from complex biology.

Biomedical Engineering meditation immunology virology

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Publications

"Comment on "Venous access site closure with vascular closure device vs. manual compression in patients undergoing catheter ablation or left atrial appendage occlusion under uninterrupted anticoagulation: a multi-centre experience on efficacy and complications".", Europace, , (2019)
"Cardiac arrest following protamine administration: a case series.", Europace, , (2019)
"System Dynamics in Remote Monitoring Service for Cardiovascular Implantable Electronic Devices.", Stud Health Technol Inform, 257, 277-282 (2019)
"Remanufactured circular mapping catheters: safety, effectiveness and cost.", J Interv Card Electrophysiol, , (2018)
"Successful percutaneous lead extraction 15 years after a failed extraction attempt.", Europace, , (2018)
"Plasticity of Mycobacterium tuberculosis NADH dehydrogenases and their role in virulence.", Proc Natl Acad Sci U S A, , (2018)
"Authors' reply: Missing key factors in nutritional assessment and bone density in children with eczema.", Hong Kong Med J, 23(6), 664-665 (2017)
"Assessment of dietary food and nutrient intake and bone density in children with eczema.", Hong Kong Med J, , (2017)
"Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis.", Proc Natl Acad Sci U S A, , (2017)
"Rapid and selective detection of viruses using virus-imprinted polymer films.", Nanoscale, , (2015)
"Smoking Cessation Strategies in Pregnancy.", J Obstet Gynaecol Can, 37(9), 791-797 (2015)
"Synthesis and biological activity of alkynoic acids derivatives against mycobacteria.", Chem Phys Lipids, , (2015)
"Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency.", Science, 6233, 448-453 (2015)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep", Science Translational Medicine, Vol 6, Issue 266, Pages 266ra171, (2014)
"A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner.", J Virol, 6, 3324-3334 (2013)
"The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge.", Antiviral Res, 3, 416-428 (2012)
"Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry.", J Infect Dis, , S973-S977 (2011)
"Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells.", Immunol Cell Biol, 7, 792-802 (2011)
"Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions.", Antimicrob Agents Chemother, 8, 3889-3898 (2011)
"Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.", J Virol, 2, 1169-1175 (2010)
"A five-amino-acid deletion of the eastern equine encephalitis virus capsid protein attenuates replication in mammalian systems but not in mosquito cells.", J Virol, 14, 6972-6983 (2008)
"Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation.", J Virol, 11, 5156-5167 (2006)
"Inhibitors of glycosphingolipid biosynthesis reduce transepithelial electrical resistance in MDCK I and FRT cells.", Am J Physiol Cell Physiol, 4, C1021-C1030 (2003)
"Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.", J Biol Chem, 14, 12128-12136 (2002)
"The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium.", Proc Natl Acad Sci U S A, 6, 3842-3847 (2002)
"Effects of a water-soluble antitumor ether phosphonoinositide, D-myo-inositol 4-(hexadecyloxy)-3(S)-methoxybutanephosphonate (C4-PI), on inositol lipid metabolism in breast epithelial cancer cell lines.", Biochem Pharmacol, 10, 1153-1158 (1999)
"A convenient synthesis of D-myo-inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and L-myo-inositol 1,4,5-trisphosphate (Ins(3,5,6)P3).", Carbohydr Res, 305(2), 171-179 (1997)

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